Researchers Develop a Test for Early Stage Ovarian Cancer


 

With funding providing by the Laura Crandall Brown Foundation and the Ovarian Cancer Institute, researchers at Georgia Tech have developed a method to detect ovarian cancer that is highly accurate in patients with Stage 1 disease.

The researchers employed high performance mass spectrometry to interrogate the serum metabolome of early-stage ovarian cancer (OC) patients and age-matched control women. The resulting spectral features were used to establish a linear support vector machine (SVM) model of 16 diagnostic metabolites that are able to identify early-stage OC with 100% accuracy in the patient cohort. The results provide evidence for the importance of lipid and fatty acid metabolism in OC and serve as the foundation of a clinically significant diagnostic test.

For now, there is not a timeline of when the test will be available publicly.

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