Can stem cells mend a broken heart? Which approach to managing carotid stenosis is the best option to help which patients avoid a stroke?
Pulmospheres, three dimensional multicellular spheroids composed of lung cells from individual patients, were shown to be effective in predicting the efficacy of medications for idiopathic pulmonary fibrosis, according to findings from UAB scientists presented in JCI Insight, a journal of the American Society for Clinical Investigation.
A new UAB study shows that, when older cancer patients were paired with trained nonmedical professionals in the form of lay navigators, there was significant decline in health care resource utilization and Medicare costs, providing an innovative model in transitioning to value-based health care on a national scale.
Researchers at the HudsonAlpha Institute for Biotechnology, along with an international team of collaborators from six countries, have identified a new genetic disorder that causes intellectual and developmental delay in children.
Investigators with The Cancer Genome Atlas Research Network, including a researcher from the UAB, have identified novel genomic characteristics of cervical cancer that will aid in the subclassification of the disease and may help target therapies that are most appropriate for each individual patient.
A study on the efficacy of surgery to remove the thymus in myasthenia gravis (MG) patients, led by researchers at UAB, has been named one of the top neurology stories of 2016 by the New England Journal of Medicine Journal Watch.
Physicians at UAB and colleagues have discovered that administering the antibiotic azithromycin alongside the standard recommended antibiotic regimen, cefazolin, reduces infection rates by 50 percent for women who have a non-elective cesarean delivery.
A team of physicians and scientists at UAB discovered that a kinase protein, mixed lineage kinase 4, also known as MLK4, plays a crucial role in survival of patient-derived brain cancer stem cells in pre-clinical animal models. The findings suggest that MLK4 could potentially be a useful target for cancer treatment.
With funding providing by the Laura Crandall Brown Foundation and the Ovarian Cancer Institute, researchers at Georgia Tech have developed a method to detect ovarian cancer that is highly accurate in patients with Stage 1 disease.
"The challenge of this is not only building the center, but attracting users across the national community and for them to become aware of what we have to offer," says Marcas Bamman, PhD, director of the new REACT Center and MR3 Network Coordinating Center at UAB.
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